Thermo Fisher Scientific Human C-Reactive Protein (CRP) Recombinant Protein
인간 C-반응성 단백질(CRP) 재조합 단백질로, E. coli에서 발현 및 고순도 정제됨. 면역학적 분석에서 양성 대조군으로 사용 가능. 염증 반응 연구 및 면역학적 기전 분석에 적합. 연구용으로만 사용.
- 카탈로그번호
- RP75527
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): Assay-dependent
- Control (Ctrl): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | E. coli |
| Amino Acid Sequence | Gln19–Pro224 |
| Class | Recombinant |
| Type | Protein |
| Purity | >95%, by SDS-PAGE under reducing conditions |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Purified |
| Storage Buffer | 20 mM Tris-HCl, pH 7.5, with 0.14 M NaCl, 2 mM CaCl₂ |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
RP-75527 contains purified recombinant human C-Reactive Protein (CRP).
It may be used as a positive control in various immunological assays.
Target Information
C-reactive protein (CRP) is a major cyclic, pentameric acute-phase protein composed of five identical, noncovalently bound, nonglycosylated subunits.
Each subunit consists of 206 amino acids with a molecular weight of approximately 24 kDa.
CRP is synthesized by the liver, and its plasma concentration increases dramatically during inflammatory processes.
It initiates the classical complement cascade, binds to nuclear components such as chromatin and histones, and plays a key role in innate immunity.
CRP functions as:
- An opsonin and activator of monocytes/macrophages
- A scavenger during cell necrosis by binding nuclear components
- A mediator in pathogen recognition and elimination
Elevated basal CRP levels are associated with increased risk of hypertension and cardiovascular disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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