Thermo Fisher Scientific Carbonic Anhydrase IX Polyclonal Antibody
Carbonic Anhydrase IX 단백질을 표적하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 ELISA에 적합하며, 고순도 Affinity Chromatography로 정제됨. Hypoxia 관련 연구 및 세포막 단백질 분석에 활용 가능.
- 카탈로그번호
- PA5120463
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 52–151 of human Carbonic Anhydrase 9 (CA9/G250) (NP_001207.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.81 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914035 |
Product Specific Information
Positive test controls include mouse liver and rat liver.
Target localization: Cell membrane, Cell projection, Nucleus, Single-pass type I membrane protein, microvillus membrane, nucleolus.
Immunogen sequence:
GSSGEDDPLG EEDLPSEEDS PREEDPPGEE DLPGEEDLPG EEDLPEVKPK SEEEGSLKLE DLPTVEAPGD PQEPQNNAHR DKEGDDQSHW RYGGDPPWPR
Target Information
Carbonic anhydrase (CA) is an enzyme that catalyzes the rapid interconversion of carbon dioxide and water into carbonic acid, protons, and bicarbonate ions. It is abundant in mammalian tissues and plays a key role in pH regulation.
CA IX, a hypoxia-inducible gene regulated by HIF-1α, is a reliable histochemical marker of hypoxia due to its membrane localization and stability.
Blocking CA IX can lead to increased cell death under hypoxic conditions, making it an important target in hypoxia-related studies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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