Thermo Fisher Scientific Migfilin-1/FBLIM1 Monoclonal Antibody (FBLIM1/4600)
인간 FBLIM1 단백질을 인식하는 마우스 단클론 항체입니다. Western blot, IHC, ICC 등 다양한 응용에 사용 가능합니다. 단백질 A/G로 정제된 무보존제 액상 형태이며, -20°C에서 보관합니다. 세포 부착 및 형태 조절 연구에 적합합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2 µg/mL |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | FBLIM1/4600 |
| Immunogen | Recombinant full-length human FBLIM1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and multiple C-terminal LIM domains. The protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. It is involved in the assembly and stabilization of actin filaments and may modulate cell adhesion, morphology, and motility. Additionally, it localizes to the nucleus and may influence cardiomyocyte differentiation through interaction with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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