Thermo Fisher Scientific Migfilin-1/FBLIM1 Recombinant Rabbit Monoclonal Antibody (FBLIM1/8189R)
인간 FBLIM1 단백질을 인식하는 재조합 토끼 단클론 항체. IHC(P) 및 IHC(PFA) 실험에 적합하며, 세포 접착 및 세포골격 연구에 활용 가능. CHO 세포에서 발현된 IgG kappa 형식으로, Protein A/G 정제 및 PBS 완충액에 보관.
- 카탈로그번호
- 54751-RBM3-Px (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Migfilin-1/FBLIM1 Recombinant Rabbit Monoclonal Antibody (FBLIM1/8189R)
Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | FBLIM1/8189R |
| Immunogen | Recombinant full-length human FBLIM1 protein (UniProt ID: Q8WUP2-1, range: 1–373 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and multiple C-terminal LIM domains. The protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. It is involved in the assembly and stabilization of actin filaments and likely plays a role in modulating cell adhesion, morphology, and motility. It can also localize to the nucleus and may influence cardiomyocyte differentiation through interaction with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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