Thermo Fisher Scientific Migfilin-1/FBLIM1 Recombinant Rabbit Monoclonal Antibody (FBLIM1/8189R)
Recombinant rabbit monoclonal antibody against human FBLIM1. IHC(P) 및 IHC(PFA) 실험에 적합하며, CHO 세포에서 발현된 단클론 항체. 단백질 A/G로 정제된 액상 형태로 제공되며, PBS(pH 7.4) 버퍼에 보존제 없이 저장. 세포 접착 및 골격 연구용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | FBLIM1/8189R |
| Immunogen | Recombinant full-length human FBLIM1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and multiple C-terminal LIM domains. The protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. It may be involved in the assembly and stabilization of actin filaments and plays a role in modulating cell adhesion, morphology, and motility. The protein also localizes to the nucleus and may affect cardiomyocyte differentiation through interaction with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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