Thermo Fisher Scientific OPRK1 Polyclonal Antibody
OPRK1 폴리클로날 항체로 인간 및 랫트 시료에 반응하며, 면역조직화학(IHC) 분석에 적합합니다. 항원 친화 크로마토그래피로 정제된 고순도 제품으로, KLH 접합 합성 펩타이드 면역원 기반입니다. 연구용으로만 사용되며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Thermo Fisher Scientific OPRK1 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 4 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide, KLH conjugated, corresponding to the second extracellular domain of human kappa-1 Opioid Receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_560425 |
Product Specific Information
- Positive control: Rat brain
Target Information
This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic, and aversive actions of synthetic opioids.
Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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