Thermo Fisher Scientific OPRD1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human delta opioid receptor (OPRD1). Validated for IHC (Paraffin) applications. High specificity and cross-reactivity with mouse and rat. Suitable for neuroscience and receptor signaling research. For research use o...
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Applications
Tested Application and Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 32 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from C-terminus of human delta Opioid receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_560422 |
Product Specific Information
- Peptide sequence identity/similarity to mouse: 81/87%
- Peptide sequence identity/similarity to rat: 75/75%
Target Information
OPRD1 (Opioid Receptor Delta 1) is involved in the regulation of anxiety, depression, and pain. It is considered a promising target for therapies addressing mood disorders and drug addiction.
Delta and kappa opioid receptors can form heterodimers, functioning synergistically.
OPRD1 expression is primarily found in the brain—high levels in the cortex, caudate, hippocampus, nucleus accumbens, and putamen; low levels in the cerebellum, hypothalamus, substantia nigra, and thalamus.
Reduced expression has been observed in the putamen and amygdala of Alzheimer’s patients and in the putamen in Parkinson’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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