Thermo Fisher Scientific OPRK1 Polyclonal Antibody
OPRK1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, 인간 및 랫트 시료에 반응합니다. IHC(P) 적용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 통증 및 오피오이드 관련 연구용으로 적합합니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 15 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from C-terminus of human Kappa Opioid Receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_560426 |
Product Specific Information
- Recommended positive controls: Rat brain
- Predicted reactivity: Peptide sequence identity/similarity to Mouse: 88/100%, Rat: 88/100%
- PA1-24535 has been successfully used in Immunohistochemistry (paraffin) procedures
Target Information
This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands and various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This receptor plays a role in pain perception and mediates hypolocomotor, analgesic, and aversive actions of synthetic opioids. Variations in this gene have been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found. A recent study provided evidence for translational readthrough and expression of an additional C-terminally extended isoform.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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