Thermo Fisher Scientific NOR-1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human NOR-1 (NR4A3). Suitable for immunohistochemistry in paraffin-embedded samples. Supplied as unconjugated liquid form at 1 mg/mL. For research use only; not for diagnostic procedures.
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Thermo Fisher Scientific NOR-1 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from modulating domain of human NR4A3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_560306 |
Product Specific Information
PA1-24536 detects NOR-1 in Human samples.
Target Information
NOR-1 (NR4A3), a nerve growth factor-like receptor, plays roles in neuronal development, T-cell apoptosis, and cancer progression. It binds to the NGFI-B response element (NBRE) and regulates the pro-opiomelanocortin (POMC) gene. NOR-1 expression is rapidly and transiently induced by various stimuli. Downregulation of NOR-1 and other NGFI-B family members correlates with drug addiction-prone behavior in Lewis rats. Three human protein isoforms have been documented: NOR-1, NOR-1β, and NOR-1 3′ variant.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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