Thermo Fisher Scientific SARS-CoV-2 Spike Protein S2 Recombinant Rabbit Monoclonal Antibody (HL237)
SARS-CoV-2 Spike Protein S2를 인식하는 recombinant rabbit monoclonal antibody. WB, IHC, ICC, ELISA 등 다양한 응용에 사용 가능. SARS-CoV 및 MERS-CoV와 교차 반응 없음. Protein A로 정제된 고순도 항체로 연구용에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 | |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | HL237 |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of SARS-CoV-2 Spike (S2). The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2890592 |
Product Specific Information
- Positive control: 293T, SARS-CoV-2 (2019-nCoV) Spike-transfected 293T cells
- Specificity: Detects SARS-CoV-2 Spike protein; does not cross-react with SARS-CoV or MERS-CoV spike proteins (based on internal testing)
Target Information
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), also known as 2019-nCoV (2019 Novel Coronavirus), causes illnesses ranging from mild cold-like symptoms to severe respiratory distress and death.
The Spike (S) Protein consists of S1 and S2 domains. The S2 domain is responsible for viral fusion with host cells.
Spike proteins play a crucial role in inducing neutralizing antibodies, T-cell responses, and protective immunity.
Diversity among coronaviruses is reflected in variations of the Spike protein, which influence receptor binding and membrane fusion mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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