Thermo Fisher Scientific Thrombospondin-1 Monoclonal Antibody (A6.1), eBioscience
인간, 마우스, 랫트의 Thrombospondin-1을 인식하는 A6.1 클론 단일클론 항체. 다양한 응용(ELISA, WB, IHC, ICC 등)에 사용 가능. 고순도(>90%)로 SDS-PAGE 검증. PBS 버퍼에 0.09% sodium azide 포함, 4°C 보관.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Thrombospondin-1 Monoclonal Antibody (A6.1), eBioscience
Thermo Fisher Scientific Thrombospondin-1 Monoclonal Antibody (A6.1), eBioscience
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-Dependent | - |
| Immunohistochemistry (IHC) | - | 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-Dependent | - |
| Immunocytochemistry (ICC/IF) | 1 µg/mL | - |
| ELISA | Assay-Dependent | - |
| Immunoprecipitation (IP) | Assay-Dependent | - |
| Functional Assay | - | 1 publication |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | A6.1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2572987 |
Product Specific Information
The A6.1 monoclonal antibody recognizes human, mouse, and rat thrombospondin-1, a member of the thrombospondin family of extracellular calcium-binding proteins.
Thrombospondin-1 is a secreted glycoprotein originally discovered in activated platelets but also expressed by endothelial cells, adipocytes, fibroblasts, macrophages, monocytes, and smooth muscle cells.
It binds extracellular matrix components such as fibronectin, integrins, and heparin, with signaling mediated through the TGF beta pathway.
Thrombospondin-1 is involved in angiogenesis, inflammation, osteogenesis, cell proliferation, and synaptogenesis during neural development.
Applications Reported: Immunoprecipitation, Western blotting, immunohistochemistry (formalin-fixed paraffin-embedded tissue), microscopy, ELISA, and immunocytochemistry.
Applications Tested:
- IHC (paraffin): ≤ 1 µg/mL using high pH antigen retrieval
- ICC: ≤ 1 µg/mL with formaldehyde or methanol fixation
Careful titration is recommended for optimal assay performance.
Purity: >90% (SDS-PAGE)
Aggregation: <10% (HPLC)
Filtration: 0.2 µm post-manufacturing filtered
Target Information
Thrombospondin is a protein from platelet α-granules composed of three identical subunits bound by interchain disulfides. It is secreted at sites of platelet activation and aggregation and participates in chemotaxis, adhesion, proliferation, and differentiation of leukocytes, fibroblasts, smooth muscle, and endothelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.