Thermo Fisher Scientific Phospho-WEE1 (Ser642) Monoclonal Antibody (T.870.10)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunoprecipitation (IP)

1:50

-

Product Specifications

Species Reactivity

Bovine, Human, Mouse, Non-human primate, Rat, Xenopus, Zebrafish

Host/Isotype

Rabbit / IgG

Class

Monoclonal

Type

Antibody

Clone

T.870.10

Immunogen

Synthetic phosphopeptide corresponding to residues surrounding pSer642 of human wee1 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:WEE1,uniProtId:P30291-1,ncbiNodeId:9606,antigenRange:642,antigenLength:646,antigenImageFileName:MA5-14806_WEE1_P30291-1_Rabbit.svg,antigenImageFileNamePDP:MA5-14806_WEE1_P30291-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Affinity chromatography

Storage buffer

0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol

Contains

<0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_10976933

Product Specific Information

It is not recommended to aliquot this antibody.

Target Information

WEE1, which is classified as a Ser/Thr kinase by sequence analysis, has been shown to inactivate multiple CDKs by tyrosine phosphorylation. Wee1 protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.