Thermo Fisher Scientific RGPD5 Polyclonal Antibody
Human RGPD5 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 연구용으로 HIV 관련 RGPD5 단백질 분석에 활용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (IHC) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 13 amino acid peptide from near the amino terminus of human RGPD5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11155435 |
Product Specific Information
A suggested positive control is human thymus tissue lysate.
PA5-20546 can be used with blocking peptide PEP-0666.
Target Information
The RANBP2-like and GRIP domain containing 5 protein (RGPD5) has high similarity to RANBP2, a large RAN-binding protein localized at the cytoplasmic side of the nuclear pore complex.
The gene coding for RGPD5 is thought to have arisen from a gene duplication event of RANBP2, as these highly homologous genes are located close to each other at chromosome 2q11–q12.
RGPD5 was identified as an HIV dependency factor (HDF), suggesting that RGPD5 may be an important drug target in HIV treatment.
At least two isoforms of RGPD5 are known to exist, of which the shorter isoform is expressed primarily in testis, while the longer of the two is expressed at low levels in a number of somatic tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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