
Thermo Fisher Scientific Histone H3.3 Polyclonal Antibody
Rabbit 폴리클로날 항체로 인간 Histone H3.3 단백질을 인식. Western blot 및 ELISA에 적합하며 높은 특이성과 재현성을 제공. 액상 형태로 PBS/glycerol buffer에 보존되며 -20°C에서 안정적 저장 가능.
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- PA587720
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Concentration: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1–136 of human H3F3B (NP_0020981) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.28 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804367 |
Product Specific Information
Immunogen sequence:
MARTKQTARK STGGKAPRKQ LATKAARKSA PSTGGVKKPH RYRPGTVALR EIRRYQKSTE LLIRKLPFQR LVREIAQDFK TDLRFQSAAI GALQEASEAY LVGLFEDTNL CAIHAKRVTI MPKDIQLARR IRGERA
Positive Samples: A-549, SW620, U-87MG, MCF7, LO2
Cellular Location: Chromosome, Nucleus
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through interactions with linker histone H1 to form higher-order chromatin structures. This gene encodes a member of the histone H3 family, located separately from other H3 genes on chromosome 6p22-p21.3. Transcripts from this gene lack polyA tails and contain a palindromic termination element.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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