Thermo Fisher Scientific PCDH1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 60-220 of human PCDH1 (NP_0025782) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PCDH1,uniProtId:Q08174-1,ncbiNodeId:9606,antigenRange:60-220,antigenLength:1060,antigenImageFileName:PA5-87731_PCDH1_Q08174-1_Rabbit.svg,antigenImageFileNamePDP:PA5-87731_PCDH1_Q08174-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.73 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804374

Product Specific Information

Immunogen sequence: VVYKVPEEQP PNTLIGSLAA DYGFPDVGHL YKLEVGAPYL RVDGKTGDIF TTETSIDREG LRECQNQLPG DPCILEFEVS ITDLVQNGSP RLLEGQIEVQ DINDNTPNFA SPVITLAIPE NTNIGSLFPI PLASDRDAGP NGVASYELQA GPEAQELFGL Q; Positive Samples: U-87MG, LO2, HeLa, SW480, BT-474; Cellular Location: Cell junction, Cell membrane, Single-pass type I membrane protein

Target Information

Protocadherin 1, also known as PCDH1 and cadherin-like protein 1, is a transmembrane protein involved in cell-cell adhesion. Protocadherin 1 belongs to a group of cadherin-like proteins termed delta1-protocadherins, which consists of protocadherin-1, -7, -9, and -11(X/Y). The delta1-protocadherins have seven extracellular cadherin-repeats, a transmembrane domain, and a cytoplasmic domain, and can be expressed in two isoforms, short or long. Expression of protocadherin 1 is regulated both temporally and spatially, and plays a role both in early development and mature tissues. In mice, it is expressed in a number of tissues and organs, including the brain, spinal cord, peripheral ganglia, inner ear, hair follicles, kidney, reproductive organs, prostate, and the seminal gland. Notably, protocadherin 1 is a susceptibility gene for Bronchial Hyperresponsiveness in humans. Expression of protocadherin 1 has also been identified on human pluripotent stem cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.