Thermo Fisher Scientific PCDH1 Polyclonal Antibody
Thermo Fisher Scientific의 PCDH1 Polyclonal Antibody는 인간 PCDH1 단백질을 인식하는 토끼 유래 다클론 항체로, Western blot 및 ELISA에 적합합니다. 세포막 단백질 분석에 유용하며, 높은 특이성과 재현성을 제공합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 60–220 of human PCDH1 (NP_0025782) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.73 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804374 |
Product Specific Information
Immunogen sequence:
VVYKVPEEQP PNTLIGSLAA DYGFPDVGHL YKLEVGAPYL RVDGKTGDIF TTETSIDREG LRECQNQLPG DPCILEFEVS ITDLVQNGSP RLLEGQIEVQ DINDNTPNFA SPVITLAIPE NTNIGSLFPI PLASDRDAGP NGVASYELQA GPEAQELFGL Q
Positive Samples: U-87MG, LO2, HeLa, SW480, BT-474
Cellular Location: Cell junction, Cell membrane, Single-pass type I membrane protein
Target Information
Protocadherin 1 (PCDH1), also known as cadherin-like protein 1, is a transmembrane protein involved in cell-cell adhesion. It belongs to the delta1-protocadherin family, which includes protocadherin-1, -7, -9, and -11(X/Y). These proteins have seven extracellular cadherin repeats, a transmembrane domain, and a cytoplasmic domain, and can be expressed in two isoforms (short or long).
Expression of PCDH1 is temporally and spatially regulated and plays a role in both early development and mature tissues. In mice, it is expressed in the brain, spinal cord, peripheral ganglia, inner ear, hair follicles, kidney, reproductive organs, prostate, and seminal gland. PCDH1 is also a susceptibility gene for bronchial hyperresponsiveness in humans and is expressed on human pluripotent stem cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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