Thermo Fisher Scientific Cdc42EP2 Polyclonal Antibody
Cdc42EP2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot과 Immunocytochemistry에 적합. Human, Mouse, Rat 반응성. 액상 형태로 1 mg/mL 농도, PBS 및 50% glycerol 보존. 연구용으로만 사용 가능.
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- PA5101502
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CDC42EP2 (Accession O14613), corresponding to amino acid residues M1–H42 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850937 |
Product Specific Information
Antibody detects endogenous levels of total BORG1.
Target Information
Cdc42, a small GTPase, regulates actin polymerization, elongation of cell shape, and cell signaling through interactions with various downstream effector proteins containing a Cdc42-binding CRIB domain.
Cdc42EP2 (Cdc42 effector protein 2), also known as BORG1 or CEP2, is a 210 amino acid intracytoplasmic protein localized to both cytoplasm and cytoskeleton.
Highly expressed in heart and present at lower levels in liver and pancreas, Cdc42EP2 interacts with Cdc42 and is thought to be involved in actin cytoskeleton organization and may influence actin filament assembly and overall cell shape.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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