Thermo Fisher Scientific Cdc42EP3 Polyclonal Antibody
인간, 마우스, 랫트 반응성의 Rabbit Polyclonal 항체로 CDC42EP3 단백질을 검출. Western blot, IHC, ICC/IF 등 다양한 응용 가능. 합성 펩타이드 면역원 기반, 액상 형태로 1 mg/mL 농도. 연구용 전용 제품.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CDC42EP3 (Accession Q9UKI2), corresponding to amino acid residues I31–H81 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850938 |
Product Specific Information
Antibody detects endogenous levels of total BORG2.
Target Information
CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with downstream effector proteins.
The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins, which contain a CRIB (Cdc42/Rac interactive-binding) domain.
Borg family proteins bind to and negatively regulate the function of CDC42. This protein can interact with CDC42 and the ras homolog gene family member Q (ARHQ/TC10).
Expression of this protein in fibroblasts induces pseudopodia formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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