
Thermo Fisher Scientific CD154 (CD40 Ligand) Monoclonal Antibody (40804)
인간 CD154(CD40 Ligand)에 특이적인 마우스 단클론 항체로, WB, IHC, Flow Cytometry, Neutralization 등 다양한 응용에 적합합니다. E. coli 유래 재조합 단백질로 면역화되었으며, 높은 순도와 낮은 엔도톡신 수준을 제공합니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 8–25 µg/mL |
| Flow Cytometry (Flow) | 0.25 µg per million cells |
| Neutralization (Neu) | Assay-Dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 40804 |
| Immunogen | E. coli-derived recombinant human CD40 Ligand/TNFSF5 (Leu50–Leu261) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609018 |
Product Specific Information
- No cross-reactivity with recombinant human CD27 Ligand, CD30 Ligand, or recombinant mouse CD40 Ligand in ELISA and Western blot assays.
- Reconstitute at 0.5 mg/mL in sterile PBS.
- Endotoxin level < 0.10 EU per 1 µg antibody (LAL method).
Target Information
CD40 Ligand (CD40-L, CD154) is a membrane glycoprotein expressed on activated T cells. It promotes B cell proliferation and immunoglobulin secretion in the presence of cytokines. CD40 Ligand also induces cytokine production and tumoricidal activity in monocytes, and co-stimulates activated T cell proliferation with IFN-γ, TNF-α, and IL-2 production.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: MA5-23829_CD154_CD40_Ligand_P29965-1_House_mouse.svg, MA5-23829_CD154_CD40_Ligand_P29965-1_House_mouse_PDP.jpeg)
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