Thermo Fisher Scientific Phospho-FGFR3 (Tyr760) Polyclonal Antibody
FGFR3 Tyr760 인산화 형태를 특이적으로 인식하는 Rabbit Polyclonal Antibody. Western blot에 최적화된 고감도 항체로 인간, 생쥐, 랫트 시료에 반응. 액상 형태로 1 mg/mL 농도, PBS/glycerol buffer에 보관하며 -20°C 저장.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-FGFR3 (Tyr760) Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human FGFR3 (Accession P22607), corresponding to amino acid residues around phosphorylated Tyr760 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817280 |
Product Specific Information
Antibody detects endogenous levels of FGFR3 only when phosphorylated at Tyr760.
Target Information
FGFR3 is a member of the FGFR family of receptor tyrosine kinases. This family regulates various cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair. FGFR family members are implicated in diseases such as cancer, rheumatoid arthritis, and diabetic retinopathy. They differ in ligand affinities and tissue distribution. FGFR3 interacts with fibroblast growth factors, initiating downstream signaling that influences mitogenesis and differentiation. Mutations in FGFR3 are linked to craniosynostosis and skeletal dysplasia. Three alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 없음)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.