
Thermo Fisher Scientific CDC37 Polyclonal Antibody
CDC37 단백질을 표적으로 하는 Thermo Fisher Scientific의 rabbit polyclonal antibody. Western blot에 적합하며, 고순도 항원 친화 크로마토그래피로 정제됨. Lyophilized 형태로 제공되며, 재구성 후 500 µg/mL 농도 유지. 세포 주기 및 신호전달 연구용.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–0.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human Cdc37 (361–376aa DPLLEAVPKTGDEKDV) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide, 0.05 mg thimerosal |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2746135 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
In S. cerevisiae, Cdc37 is an important regulator of the cell division cycle through its action on cyclin-dependent kinases (CDKs). It is also associated with signaling pathways and kinases unrelated to cell cycle control, including v-Src, casein kinase II, MPS1 kinase, and the sevenless receptor tyrosine kinase.
Cdc37 (also known as p50) interacts with many proteins associated with HSP90, including Src-family kinases (Fyn, Yes, Fes, Lck, Fgr), Raf, and pp60v-src. It functions as a chaperone independently and in concert with HSP90, and is necessary for the binding of HSP90 to Cdk4.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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