
Thermo Fisher Scientific DUSP22 Polyclonal Antibody
인간 DUSP22 단백질을 인식하는 Rabbit Polyclonal Antibody로 IHC(P)에서 1–7 µg/mL 농도로 사용 가능. MAP kinase 신호전달 연구에 적합하며, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 제공되며 단기 4°C, 장기 -20°C 보관 권장.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1–7 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 20 amino acid peptide from internal region of human DUSP22 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550868 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gorilla, Gibbon, Elephant (100%); Monkey, Marmoset, Horse (95%); Hamster, Dog, Bat, Rabbit (90%).
Target Information
Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by various stimuli and mediate physiological and pathological cellular changes.
Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, selective for dephosphorylating phosphothreonine and phosphotyrosine residues within MAP kinases.
DSP gene expression is induced by growth factors and cellular stresses, negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK, and p38.
DUSP22 dephosphorylates ERK2 MAP kinase and JNK, showing highest expression in thymus and detectable levels in monocytes and lymphocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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