Thermo Fisher Scientific RSK3 Polyclonal Antibody
Rat에서 반응하는 RSK3 단백질에 대한 Goat Polyclonal Antibody. Western blot에 최적화되어 있으며, 0.01–0.03 µg/mL 농도로 사용 가능. TBS buffer(pH 7.3)와 0.5% BSA 포함, -20°C에서 보관. 성장인자 신호전달 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.01–0.03 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-EYLSPNQLSRQDVH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933054 |
Product Specific Information
- This antibody is expected to recognize both reported isoforms (NP_066958.2; NP_001006933.1).
- Tested in Peptide ELISA: antibody detection limit dilution 1:64,000.
Target Information
RPS6KA2 (RSK3) serine/threonine kinase is a member of the ribosomal S6 kinase (RSK) family. It acts as a signal-transducing intermediate in cellular responses to various growth factors. The protein is expressed in many tissues, with higher levels in lung and skeletal muscle.
The p90 ribosomal S6 kinases (RSK1–4) are downstream components of the ERK/MAPK cascade. Loss of RSK2 activity in humans results in Coffin-Lowry syndrome, characterized by mental retardation and growth deficits, potentially affecting G-protein coupled signaling regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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