Thermo Fisher Scientific GPR120 Polyclonal Antibody
Human GPR120 인식하는 goat polyclonal antibody로, IHC(P)에서 2–4 µg/mL 농도로 사용 가능. Peptide ELISA에서 높은 민감도(1:16,000) 검출 한계. 액상 형태로 TBS(pH 7.3) buffer 및 0.5% BSA 포함. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2–4 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-YSESHQIRVSQQD (aa 247–259) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933050 |
Product Specific Information
- Tested in Peptide ELISA: antibody detection limit dilution 1:16,000
- Preliminary analysis showed no signal in Western Blot
Target Information
An EST for GPR120 has been isolated from a human colon cancer library.
G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules, with more than a thousand members predicted to exist.
All GPCRs share a structural motif consisting of seven membrane-spanning helices and exist in both active and inactive forms.
Activating ligands induce conformational changes leading to signaling via G-proteins and downstream effectors.
Negative regulation of GPCRs plays an important role in cellular physiology and drives pharmacological research for new drug candidates.
Notable GPCR-targeted drugs include Zyprexa (Eli Lilly) and Claritin (Schering-Plough), major pharmaceuticals in mental health and allergy treatment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-142402_GPR120_Q5NUL3-2_Goat.svg / PA5-142402_GPR120_Q5NUL3-2_Goat_PDP.jpeg)
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