Thermo Fisher Scientific CHRNA7 Polyclonal Antibody
CHRNA7 단백질을 표적으로 하는 Thermo Fisher Scientific의 염소 유래 다클론 항체. 인간 및 랫트 반응성, IHC(P) 검증 완료. CHRNA7-FAM7A 융합 이소폼에도 반응하며, 고순도 액상 형태로 제공. 연구용으로만 사용 가능.
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Thermo Fisher Scientific CHRNA7 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 3–6 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host/Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence KRPGEDKVRPACQHKQ |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2933053 |
Product Specific Information
- This antibody also reacts with CHRNA7-FAM7A fusion isoform 1 (NP_647536.1) and isoform 2 (NP_683709.1).
- Tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
Chromosome 15 encodes over 700 genes and comprises nearly 3% of the human genome. CHRFAM7A, a fusion protein comprised of FAM7A and AChR alpha7, is encoded by the CHRFAM7A gene, located on a region of human chromosome 15 associated with several neuropsychiatric disorders such as schizophrenia and bipolar affective disorder.
CHRFAM7A (also known as D-10 or CHRNA7) is a 412 amino acid multi-pass membrane protein belonging to the nicotinic acetylcholine receptor (nAChR) subfamily of ligand-gated ion channel proteins, which mediate signal transmission at synapses.
CHRFAM7A is expressed in the hippocampus, and alternative splicing of the CHRFAM7A gene produces two splice variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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