Thermo Fisher Scientific TNFR2 Monoclonal Antibody (HM102), FITC
TNFR2 단백질을 인식하는 HM102 클론의 FITC 결합 단일클론 항체. Western blot, IHC, Flow cytometry 등 다양한 응용 가능. TNF-α 반응을 강화하는 기능적 항체로 연구용에 적합. 4°C 암소 보관, 액상 형태.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:50 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:50 |
| Flow Cytometry (Flow) | 1:50 |
| Immunoprecipitation (IP) | 1:50 |
| Functional Assay (Functional) | 1:50 |
| Inhibition Assays (IA) | 1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rat / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | HM102 |
| Immunogen | Recognizes the extracellular part of the Tumor Necrosis Factor Receptor type I |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Wet ice |
| RRID | AB_3093264 |
Additional Formats
- Unconjugated (Cat. No. MA5-49128)
- Biotin (Cat. No. MA5-49129)
- Custom conjugation available upon request
Product Specific Information
This antibody is an agonistic receptor modulating antibody. It enhances in vitro TNF alpha responses by increasing the affinity of the soluble form of TNF-alpha for TNF-RII.
Target Information
TNFR2 (tumor necrosis factor receptor superfamily member 1B) is a receptor with high affinity for TNFSF2/TNF-alpha and lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. TNFR2 mediates most of the metabolic effects of TNF-alpha.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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