Thermo Fisher Scientific TNFR2 Monoclonal Antibody (HM102)
Mouse TNFR2 단백질을 인식하는 Rat IgG2a 모노클로날 항체로, TNF-α 반응을 강화하는 기능적 연구용 시약입니다. WB, IHC(F), Flow, IP, Functional, IA 등 다양한 실험에 적용 가능하며, 4°C에서 보관됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:50 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:50 |
| Flow Cytometry (Flow) | 1:50 |
| Immunoprecipitation (IP) | 1:50 |
| Functional Assay (Functional) | 1:50 |
| Inhibition Assays (IA) | 1:50 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rat / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | HM102 |
| Immunogen | The monoclonal antibody HM102 recognizes the extracellular part of the Tumor Necrosis Factor Receptor type I (TNFRI) of the membrane-bound as well as the soluble receptor. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 0.1% BSA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
| RRID | AB_3091109 |
Additional Formats
Product Specific Information
The antibody is an agonistic receptor modulating antibody. It enhances in vitro TNF-alpha responses by increasing the affinity of the soluble form of TNF-alpha for TNF-RII.
Target Information
TNFR2 (tumor necrosis factor receptor superfamily member 1B) is a receptor with high affinity for TNFSF2/TNF-alpha and lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. TNFR2 mediates most of the metabolic effects of TNF-alpha.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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