Thermo Fisher Scientific NR2C1 Monoclonal Antibody (OTI3A4), TrueMAB

Applications

• Western Blot (WB): Tested dilution 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

This gene encodes a nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD), typical for members of the steroid/thyroid hormone receptor superfamily.
NR2C1 functions as a ligand-inducible transcription factor regulating gene expression by binding to specific DNA sequences within promoters of target genes.
Multiple alternatively spliced transcript variants have been reported, though the full-length nature of some variants remains undetermined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.