Thermo Fisher Scientific Zic-1 Polyclonal Antibody
Zic-1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체입니다. Western blot, IHC, ELISA 등 다양한 응용에 적합하며, 인간 및 생쥐 시료에 반응합니다. 고순도 IgG로 정제되어 안정적이며 장기 보관이 가능합니다.
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Thermo Fisher Scientific Zic-1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:5,000 |
| Immunohistochemistry (IHC) | 1:400 |
| ELISA | 1:10,000–1:50,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Whole rabbit serum produced by repeated immunizations with an 18 aa synthetic peptide near the N-terminus of mouse Zic-1. This domain is completely conserved in human ZIC-1. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Ion-exchange chromatography |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Store vial at -20°C prior to opening.
- Aliquot contents and freeze at -20°C or below for extended storage.
- Avoid cycles of freezing and thawing.
- Centrifuge product if not completely clear after standing at room temperature.
- Stable for several weeks at 4°C as an undiluted liquid.
- Dilute only prior to immediate use.
This is an IgG preparation of whole rabbit antiserum purified by a multi-step process including delipidation, salt fractionation, and ion-exchange chromatography followed by extensive dialysis.
This antibody is directed against Zic-1 from mouse and also detects human Zic-1. Cross-reactivity with other species is likely but not determined.
Target Information
The ZIC1 gene encodes a member of the ZIC family of C2H2-type zinc finger proteins, which are important in development. Aberrant expression is observed in medulloblastoma, a childhood brain tumor. The gene is closely linked to ZIC4 on chromosome 3 and encodes a transcription factor that can bind and transactivate the apolipoprotein E gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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