Thermo Fisher Scientific beta-2-Microglobulin Polyclonal Antibody
Human beta-2-Microglobulin 단백질을 항원으로 제작된 Rabbit Polyclonal Antibody. 다양한 응용 분야(WB, IHC, ICC, ELISA, IP)에 사용 가능. 고순도 IgG 분획으로 제조되어 높은 특이성과 안정성 제공. 연구용으로만 사용.
- 카탈로그번호
- 200-401-141xxxxx (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific beta-2-Microglobulin Polyclonal Antibody
Thermo Fisher Scientific beta-2-Microglobulin Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:200 |
| ELISA | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 1:200–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Human beta-2-Microglobulin protein isolated from urine |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Ion-exchange chromatography |
| Storage Buffer | 0.02M potassium phosphate (pH 7.2), 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C and avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Store vial at 4°C prior to restoration. For extended storage, aliquot contents and freeze at -20°C or below. Avoid freeze/thaw cycles. Centrifuge if not clear after standing at room temperature. Stable for several weeks at 4°C as undiluted liquid. Dilute only prior to immediate use.
This antibody is purified from monospecific antiserum by delipidation, salt fractionation, and ion-exchange chromatography, followed by dialysis. Immunoelectrophoresis shows a single precipitin arc against anti-Peroxidase and anti-Rabbit Serum, as well as purified and partially purified human beta-2-Microglobulin. Cross-reactivity with other sources is unknown.
Target Information
Beta-2-microglobulin (B2M) is a 12–14 kDa subunit of MHC class I molecules. It is associated with HLA Class I antigens expressed on lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial and epithelial cells, but absent on erythrocytes. Found both membrane-bound and free in plasma, B2M has sequence homology to immunoglobulin constant regions and a beta-pleated sheet structure. It plays roles in antigen presentation, TCR signaling, and CD8+ cell signaling. The B2M gene is located on chromosome 15; mutations can cause hypercatabolic hypoproteinemia. Beta-2-microglobulin levels serve as renal function markers and as prognostic indicators for HIV infection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.