Thermo Fisher Scientific SRC Monoclonal Antibody (4F1E8)
SRC 단백질을 타겟으로 하는 Mouse IgG2b 단일클론 항체로, Western Blot 및 ELISA에 적합합니다. 인간 시료와 반응하며, 비결합형 액상 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4F1E8 |
| Immunogen | Purified recombinant fragment of SRC (aa10–193) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10980047 |
Product Specific Information
MA5-15398 targets SRC in indirect ELISA and WB applications, showing reactivity with human samples.
The immunogen is a purified recombinant fragment of SRC (aa10–193) expressed in E. coli.
Target Information
SRC is a cytoplasmic tyrosine kinase and proto-oncogene involved in regulation of embryonic development and cell growth. It associates with cytoplasmic regions of various cell surface receptors to facilitate signal transduction and plays roles in cytoskeletal organization, cell cycle regulation, and apoptosis.
In humans, SRC is encoded on chromosome 20. Its activity is regulated by phosphorylation at Tyr416 (activation) and Tyr527 (inhibition). Mutations in SRC may contribute to malignant progression of colon cancer. Two transcript variants encoding the same SRC protein have been identified.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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