Thermo Fisher Scientific Myeloperoxidase Monoclonal Antibody (2C7)
인간 Myeloperoxidase를 인식하는 Mouse IgG1 단클론 항체로 다양한 면역분석(IHC, ICC, WB, Flow)에 사용 가능. 비결합형 액상 형태로 1 mg/mL 농도, Protein A 정제. 골수 조직을 양성 대조로 권장하며 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | - |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:500–1:1,000 | - |
| Immunohistochemistry (Frozen) (IHC-F) | 1:1,000–1:5,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100 | 1 publication |
| Flow Cytometry (Flow) | 1:50–1:100 | - |
| Miscellaneous PubMed (Misc) | - | 1 publication |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2C7 |
| Immunogen | Human myeloperoxidase |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1956783 |
Product Specific Information
A suggested positive control for this product is bone marrow.
Target Information
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation and is a major component of neutrophil azurophilic granules. It is produced as a single-chain precursor and subsequently cleaved into light and heavy chains. The mature MPO forms a tetramer composed of two light and two heavy chains. This enzyme generates hypohalous acids essential for neutrophil microbicidal activity. Diseases associated with MPO include Myeloperoxidase Deficiency and Familial Alzheimer’s Disease type 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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