Thermo Fisher Scientific LRRK2 Polyclonal Antibody

Applications and Tested Dilution

• Western Blot (WB): 1:500

Product Specifications

Product Specific Information

• The target sequence has 88% sequence homology with mouse and rat.
• Suggested positive control: human brain lysate.

Target Information

LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Mutations in LRRK2 have been associated with Parkinson’s disease. LRRK2 is a member of the leucine-rich repeat kinase family and encodes a protein with an ankyrin repeat region, a leucine-rich repeat domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.