Thermo Fisher Scientific CD8 beta Monoclonal Antibody (3.4.1)

Applications

Flow Cytometry (Flow)

• Tested Dilution: 1 µg/1 million cells

Product Specifications

Additional Formats

• Biotin
• FITC
• PE
• Request custom conjugation

Product Specific Information

MA1-70040 detects CD8b in rat samples.
MA1-70040 has been successfully used in flow cytometry procedures.
The MA1-70040 immunogen is rat/mouse T cell hybrids expressing CD8.

Target Information

The CD8B antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system.
The CD8 antigen acts as a coreceptor with the T-cell receptor to recognize antigens presented by APCs in the context of class I MHC molecules.
The functional coreceptor can be a homodimer (two alpha chains) or a heterodimer (one alpha and one beta chain).
Both alpha and beta chains share significant homology with immunoglobulin variable light chains.
This gene encodes the CD8 beta chain isoforms, with multiple alternatively spliced transcript variants.
A pseudogene located on chromosome 2 has also been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.