Thermo Fisher Scientific MYCBP2 Polyclonal Antibody
Rabbit polyclonal antibody against human MYCBP2. Validated for ICC/IF applications. Recognizes recombinant MYCBP2 protein. Supplied in liquid form with PBS and glycerol. Suitable for research use only.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MYCBP2. Recombinant protein control fragment (Product # RP-108434) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2791545 |
Product Specific Information
Immunogen sequence:
CYHPAKPFQS QLPSVKEGIS EDLPVKMPCL YLQTLARHHH ENFVGYQDDN LFQDEMRYLR STSVPAPYIS VTPDASPNVF EEPESNMKSM PPSL
Target Information
This gene encodes an E3 ubiquitin-protein ligase and a member of the PHR (Phr1/MYCBP2, highwire, and RPM-1) family of proteins. It plays a role in axon guidance and synapse formation in the developing nervous system. In mammalian cells, MYCBP2 regulates the cAMP and mTOR signaling pathways and may also regulate autophagy. Reduced expression of this gene has been observed in acute lymphoblastic leukemia patients, and a mutation has been identified in patients with a rare inherited vision defect.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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