Thermo Fisher Scientific MYCBP2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human MYCBP2. Recombinant protein control fragment (Product #RP-108434). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MYCBP2,uniProtId:O75592-1,ncbiNodeId:9606,antigenRange:3364-3457,antigenLength:4678,antigenImageFileName:PA5-84393_MYCBP2_O75592-1_Rabbit.svg,antigenImageFileNamePDP:PA5-84393_MYCBP2_O75592-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.10 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2791545

Product Specific Information

Immunogen sequence: CYHPAKPFQS QLPSVKEGIS EDLPVKMPCL YLQTLARHHH ENFVGYQDDN LFQDEMRYLR STSVPAPYIS VTPDASPNVF EEPESNMKSM PPSL

Target Information

This gene encodes an E3 ubiquitin-protein ligase and member of the PHR (Phr1/MYCBP2, highwire and RPM-1) family of proteins. The encoded protein plays a role in axon guidance and synapse formation in the developing nervous system. In mammalian cells, this protein regulates the cAMP and mTOR signaling pathways, and may additionally regulate autophagy. Reduced expression of this gene has been observed in acute lymphoblastic leukemia patients and a mutation in this gene has been identified in patients with a rare inherited vision defect.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.