Thermo Fisher Scientific NFYA Polyclonal Antibody
Rabbit polyclonal antibody recognizing human NFYA, validated for WB and IHC(P). Supplied as liquid at 1 mg/mL concentration. Recommended positive control: Jurkat. Predicted cross-reactivity with multiple species. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–2.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide region of human NFYA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_560304 |
Product Specific Information
- Recommended positive controls: Jurkat
- Predicted reactivity: Cow 100%; Dog 100%; Guinea Pig 100%; Horse 100%; Mouse 100%; Rabbit 100%; Rat 100%
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The SMN1 gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements, making it prone to rearrangements and deletions. The sequence complexity has made it difficult to determine the organization of this genomic region. The telomeric and centromeric copies of this gene are nearly identical and encode the same protein, survival motor neuron protein. The SMN complex plays a catalytic role in the assembly of small nuclear ribonucleoproteins, the building blocks of the spliceosome. Mutations in the SMN1 gene are known to cause spinal muscular atrophy types 1 and 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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