Thermo Fisher Scientific STIM2 Polyclonal Antibody
STIM2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunoprecipitation에 사용 가능. 인간 STIM2의 650–700 아미노산 영역을 면역원으로 제작. 액상 형태로 제공되며, 4°C에서 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 650 to 700 of Human Stromal Interaction Molecule 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
In T lymphocytes, Ca++ entry following antigen-receptor binding occurs through store-operated Ca++-release-activated Ca++ (CRAC) channels, composed of ORAI1 and STIM1. STIM1 functions as a Ca++ sensor, activating CRAC channels by migrating to the plasma membrane from ER-like Ca++ stores.
STIM2, a related molecule, inhibits STIM1-mediated Ca++ entry and can form complexes with STIM1, suggesting a coordinated role in regulating Ca++ influx. At least three isoforms of STIM2 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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