Thermo Fisher Scientific CELSR1 Polyclonal Antibody
CELSR1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체입니다. Western blot 및 Immunoprecipitation에 사용 가능하며, 인간 시료에 반응합니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 2775 to 2825 of human Cadherin, EGF LAG Seven-Pass G-Type Receptor 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
CELSR1 is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic type cadherins that do not interact with catenins. These cadherins are located at the plasma membrane and contain:
- Nine cadherin domains
- Seven epidermal growth factor-like repeats
- Two laminin A G-type repeats
They also possess seven transmembrane domains, unique to this subfamily. CELSR1 is thought to act as a receptor involved in contact-mediated communication, with cadherin domains functioning as homophilic binding regions and EGF-like domains participating in cell adhesion and receptor-ligand interactions. This gene is developmentally regulated and neural-specific, playing a role in early embryogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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