Thermo Fisher Scientific Granzyme B Monoclonal Antibody (351927), PE
인간 Granzyme B를 인식하는 마우스 단클론 항체로, PE 형광표지되어 유세포분석(Flow Cytometry)에 적합합니다. 높은 특이성과 교차반응 없음. Protein A/G 정제, 4°C 암소 보관, 연구용 전용 시약.
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Thermo Fisher Scientific Granzyme B Monoclonal Antibody (351927), PE
Applications
- Flow Cytometry (Flow)
Tested Dilution
- 10 µL per million cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 351927 |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human Granzyme B (Gly19–Tyr247) |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | Buffered saline solution with BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609545 |
Additional Formats
- Alexa Fluor 488
- PerCP
- Custom conjugation available
Product Specific Information
This antibody does not cross-react with recombinant human Granzyme A, Granzyme H, recombinant mouse Granzyme B, Granzyme C, Granzyme D, or Granzyme G.
Target Information
Granzyme B is a serine protease found in the granules of cytotoxic T cells and NK cells. It plays a crucial role in inducing apoptosis in target cells through caspase activation and mitochondrial pathways. Granzyme B interacts with the mannose 6-phosphate receptor, functioning as a death receptor during cytotoxic T cell-induced apoptosis. It is one of several granzymes (A–G) identified in mouse CTLs and NK cells, with fewer cloned in humans.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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