Thermo Fisher Scientific CD144 (VE-cadherin) Recombinant Rabbit Monoclonal Antibody (JJ0941)

Applications

Western Blot (WB)

• Tested Dilution: 1:1,000–1:5,000

Product Specifications

Product Specific Information

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages include:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broader immunoreactivity to diverse targets due to larger rabbit immune repertoire

Target Information

VE-cadherin is a member of the cadherin superfamily located in a six-cadherin cluster on chromosome 16. It is involved in loss of heterozygosity events in breast and prostate cancer.
VE-cadherin is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region, and a conserved cytoplasmic tail. It functions as a classic cadherin, mediating homophilic adhesion, and plays an important role in endothelial cell biology by controlling cohesion and organization of intercellular junctions.
An alternative splice variant has been described, but the full-length sequence has not been determined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지