Thermo Fisher Scientific STIM1 Polyclonal Antibody
STIM1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 적합하며 인간, 마우스, 랫트에 반응. 항원 친화 크로마토그래피로 정제, 1 mg/mL 농도, 액상 형태로 4°C 보관.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Assay-dependent
Immunoprecipitation (IP)
- 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 550 and 600 of Human Stromal Interaction Molecule 1 (STIM1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with Mouse and Rat
Target Information
STIM1 (stromal interacting molecule 1; also known as GOK) acts as a sensor of calcium depletion within the endoplasmic reticulum and transduces the signal to Orai1, the presumptive CRAC channel at the plasma membrane.
Upon decrease of luminal calcium concentration, STIM1 oligomerizes and induces Orai1 to enable entry of extracellular calcium into the cytoplasm.
STIM1 also associates with growing ends of microtubules and is involved in endoplasmic reticulum tubule extension.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
제품 이미지
(A303-413A_STIM1_Q13586-1_Rabbit.svg, A303-413A_STIM1_Q13586-1_Rabbit_PDP.jpeg)
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