Thermo Fisher Scientific STIM1 Polyclonal Antibody
STIM1 단백질을 인식하는 Thermo Fisher Scientific의 다클론 항체로, Western blot과 Immunoprecipitation에 사용 가능. 인간에 반응하며 마우스, 랫, 소에서도 예측 반응. 항원 친화 크로마토그래피로 정제된 액상 형태, 4°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,500
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 635 and 685 of Human Stromal Interaction Molecule 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, and Bovine
Target Information
STIM1 (stromal interacting molecule; also known as GOK) acts as a sensor of calcium depletion within the endoplasmic reticulum and transduces the signal to Orai1, the presumptive CRAC channel at the plasma membrane. Following decrease of luminal calcium concentration, STIM1 oligomerizes and induces Orai1 to enable entry of extracellular calcium into the cytoplasm. However, the precise mechanism of STIM1-Orai1 interaction has not been elucidated yet. Many questions also remain to be solved around STIM1 functional distribution. It turns out that STIM1 associates with growing ends of microtubules and is involved in endoplasmic reticulum tubule extension.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: A303-414A_STIM1_Q13586-1_Rabbit.svg, A303-414A_STIM1_Q13586-1_Rabbit_PDP.jpeg)
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