Thermo Fisher Scientific SRAG Polyclonal Antibody
Rabbit polyclonal antibody targeting human SRAG (CHTOP) region 198–248. Suitable for WB and IP applications. Predicted cross-reactivity with mouse, rat, and bovine. Supplied as unconjugated liquid form at 1 mg/mL, stored at 4 °C.
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- A303412Ax (2개 옵션)
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 198 and 248 of Human Small Protein Rich in Arginine and Glycine (CHTOP) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4 °C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, and Bovine.
Target Information
CHTOP is a small nuclear protein characterized by an arginine- and glycine-rich region. It may play a role in regulating fetal globin gene expression and activating estrogen-responsive genes.
Studies indicate that CHTOP binds 5-hydroxymethylcytosine (5hmC) and associates with the methylosome complex, promoting methylation of histone H4 (H4R3) and activation of genes involved in glioblastomagenesis.
Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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