Thermo Fisher Scientific ZC3H8 Polyclonal Antibody
인간 ZC3H8 단백질을 인식하는 Rabbit Polyclonal Antibody. Western blot 및 IHC(P) 검증 완료. 항원 친화 크로마토그래피로 정제된 액상 형태로 제공. 연구용으로만 사용 가능.
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Thermo Fisher Scientific ZC3H8 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:2,500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ZC3H8. Recombinant protein control fragment (Product #RP-96119). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2649818 |
Product Specific Information
Immunogen sequence:
KSRSKDYDVY SDNDICSQES EDNFAKELQQ YIQAREMANA AQPEESTKKE GVKDTPQAAK Q
Highest antigen sequence identity to the following orthologs:
- Mouse: 72%
- Rat: 71%
Target Information
Zinc-finger CCCH domain-containing protein 8 (ZC3H8) acts as a transcriptional repressor of the GATA3 promoter.
It is a sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene.
ZC3H8 induces thymocyte apoptosis when overexpressed, suggesting a role in regulation of thymocyte homeostasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-57066_ZC3H8_Q8N5P1-1_Rabbit.svg, PA5-57066_ZC3H8_Q8N5P1-1_Rabbit_PDP.jpeg)
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