Thermo Fisher Scientific IL-5 Recombinant Rabbit Monoclonal Antibody (R013)
Human IL-5에 특이적인 Recombinant Rabbit Monoclonal Antibody로 높은 특이성과 재현성을 제공. ELISA 및 중화 실험에 적합하며, 보존제가 없는 액상 형태. 장기 보관 시 -20°C에서 보관 권장.
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- MA529367
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- pk
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Applications
ELISA
- Tested Dilution: 0.1–1 µg/mL
Neutralization
- Tested Dilution: 2–8 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | R013 |
| Immunogen | Recombinant Human IL-5/IL5/Interleukin 5 protein (Ile20–Ser134) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.67 mg/mL |
| Purification | Protein A |
| Storage Buffer | Histidine/arginine, pH 6, with 120 mM NaCl, 0.02% Tween 80 |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2785242 |
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
This antibody has specificity for Human IL-5/IL5/Interleukin 5.
Target Information
IL-5 is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. It regulates eosinopoiesis, eosinophil maturation, and activation. Elevated IL-5 production is associated with asthma and hypereosinophilic syndromes.
The IL-5 receptor is a heterodimer; its beta subunit is shared with receptors for IL3 and CSF2 (GM-CSF). IL-5, IL4, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q31, coordinated by long-range regulatory elements.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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