Thermo Fisher Scientific Kallikrein 11 Recombinant Rabbit Monoclonal Antibody (121)
Human KLK11 단백질을 인식하는 토끼 유래 재조합 단클론 항체입니다. Western blot, ELISA, IP에 적합하며 높은 특이성과 재현성을 제공합니다. 방부제 무첨가로 세포 배양 기반 실험에 적합합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:25,000–1:50,000 |
| Immunoprecipitation (IP) | 0.2–1 µL/mg of lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 121 |
| Immunogen | Recombinant Human KLK-11 protein (Met1–Asn250) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2785250 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to the larger rabbit immune repertoire
This antibody has specificity for Human KLK-11 (Kallikrein 11).
Target Information
Hippostasin, also known as KLK11, is a kallikrein-like serine protease with two alternatively spliced isoforms: brain-type and prostate-type. It plays roles in the prostate, including reproductive and tumorigenic functions. Elevated serum KLK11 levels have been observed in 70% of women with ovarian cancer and 60% of men with prostate cancer. Analysis of the KLK11 biomarker in serum may assist in the diagnosis and monitoring of ovarian and prostatic carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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