Thermo Fisher Scientific SEPN1 Polyclonal Antibody
Thermo Fisher Scientific의 SEPN1 폴리클로날 항체는 Mouse 반응성을 가지며 Rabbit IgG로 제작된 비결합형 액상 항체입니다. Western blot에 적합하며, SEPN1 단백질 연구에 활용됩니다. Affinity chromatography로 정제되었고, 안정적인 저장 조건을 제공합니다.
- 카탈로그번호
- PA569493
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region of mouse SEPN1 (aa 501–550) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2691251 |
Product Specific Information
This target displays homology in the following species:
Cow: 86%
Guinea Pig: 86%
Horse: 86%
Human: 100%
Mouse: 86%
Rat: 86%
Target Information
SEPN1 is a selenoprotein that contains a selenocysteine (Sec) residue at its active site. Mutations in the SEPN1 gene cause the classical phenotype of multiminicore disease and congenital muscular dystrophy with spinal rigidity and restrictive respiratory syndrome.
The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3′ UTR of selenoprotein genes contains a stem-loop structure (SECIS) necessary for recognition of UGA as a Sec codon rather than a stop signal.
Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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