Thermo Fisher Scientific Cathepsin V Polyclonal Antibody
인간 Cathepsin V 단백질을 인식하는 염소 유래 Polyclonal 항체. Western blot, IHC, Neutralization에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS와 trehalose 완충액에 동결건조 형태로 제공. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–15 µg/mL |
| Neutralization (Neu) | 2.2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human Cathepsin V (Val18–Val334) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2610132 |
Product Specific Information
- In direct ELISAs, approximately 15% cross-reactivity with recombinant human Cathepsin C is observed.
- Less than 5% cross-reactivity with rhCathepsin A, D, X/Z/P, S, and L.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Cathepsin V (CTSU, CTSV, CATL2, cathepsin U, cathepsin L2) is a lysosomal cysteine proteinase that influences corneal physiology and mediates degradation of invariant chain in the human thymus. It is expressed in corneal epithelium, activated macrophages, and certain carcinomas such as colorectal and breast cancer. A 1.8-kb mRNA to Cathepsin V is present in normal human thymus and testis. Cathepsin V belongs to the peptidase C1 family. Cysteine proteinases are synthesized as preproenzymes and processed to proenzymes, which are targeted to lysosomes or secretory pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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