Thermo Fisher Scientific IL-34 Monoclonal Antibody (1D12)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunocytochemistry (ICC/IF)

1:200-1:1,000

-

Flow Cytometry (Flow)

1:200-1:400

-

ELISA (ELISA)

1:10,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

1D12

Immunogen

Purified recombinant fragment of human IL34 expressed in E. Coli.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

ascites

Contains

0.03% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2538569

Product Specific Information

MA5-17098 targets IL34 in indirect ELISA, FACS, ICC, IF, and WB applications and shows reactivity with Human samples.

The MA5-17098 immunogen is purified recombinant fragment of human IL34 expressed in E. Coli.

MA5-17098 detects IL34 which has a predicted molecular weight of approximately 27.5kDa.

Target Information

IL-34 is secreted as a dimeric protein and currently belongs to no known cytokine family. It signals via the M-CSF Receptor, also known as CSF-1R and CD115, which is shared with M-CSF. IL-34 has no amino acid sequence homology to M-CSF, but they exhibit similarities in secondary structure and share overlapping functions. IL-34 has been shown to promote myeloid survival, proliferation, and differentiation, and to play a role in osteoclast formation. IL-34 expression has been detected in various tissues and is most abundant in the spleen.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.