Thermo Fisher Scientific PHIP Polyclonal Antibody
PHIP 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IP에 최적화되어 있습니다. 인간 PHIP의 1771–1821번 잔기 영역을 면역원으로 사용하며, 4°C에서 보관, Wet ice로 배송됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1771 and 1821 of human pleckstrin homology domain interacting protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
- 본 제품의 권장 유효기간은 수령일로부터 1년입니다.
- 100% 서열 일치 기준으로 Mouse에서도 반응할 것으로 예측됩니다.
Target Information
PHIP (pleckstrin homology domain interacting protein), also known as NDRP or WDR11, is a 1,821 amino acid protein containing eight N-terminal WD40 repeats and two bromodomains. It is expressed in skeletal muscle (cytosol and nucleus) and primary beta cells (nucleus), functioning as a transcriptional activator. PHIP interacts with insulin receptor substrate (IRS) family proteins, which mediate insulin receptor signaling and are important for beta cell proliferation and survival. PHIP associates with the PH domain of IRS-1, linking IRS-1 to insulin receptors and playing a vital role in insulin signaling regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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