Thermo Fisher Scientific CD14 Monoclonal Antibody (MEM-18), FITC
CD14 단백질을 인식하는 MEM-18 클론의 FITC 결합 단일클론 항체로, 인간 및 비인간 영장류 세포 분석에 적합. 유세포분석(Flow Cytometry)에 최적화되어 있으며, 498/517 nm 형광 특성. 액상 형태로 PBS/BSA 완충액에 보존, 4°C 암소 저장.
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Applications
- Flow Cytometry (Flow): 20 µL / 1×10⁶ cells
- View publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MEM-18 |
| Immunogen | Human urinary proteins from the urine of a patient suffering from proteinuria |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1071271 |
Additional Formats
Product Specific Information
This antibody reacts with CD14, a 53–55 kDa GPI-linked extracellular membrane glycoprotein expressed on monocytes, macrophages, and weakly on granulocytes; also expressed by most tissue macrophages.
In human, the epitope recognized by MEM-18 is located between amino acids 57–64.
Target Information
CD14 is a 55 kDa GPI-anchored glycoprotein expressed on mature monocytes, macrophages, and neutrophils.
It functions as a multifunctional lipopolysaccharide receptor and is released into serum in both secreted and cleaved forms.
CD14 binds LPS in a reaction catalyzed by LBP and plays a role in immune response modulation, apoptosis binding, and inflammatory regulation.
Alternative splicing results in multiple transcript variants encoding the same isoform.
Diseases associated with CD14 dysfunction include Mycobacterium chelonae infection and Croup.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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